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Haiyuan Zhang

Currently at UCLA

Current Research

Drug and gene delivery in cell-based nanopatterning

Education and Experience

Postdoctoral Fellow
March 2009-Present
Department of Mechanical and Aerospace Engineering
Univeristy of California, Los Angeles

Postdoctoral Fellow
March 2008-Februray 2009
Department of Chemical and Biological Engineering
Renselaer Polytechnic Institute

Postdoctoral Fellow
November 2005- Februrary 2008
School of Medicine
Wayne State University

Ph.D August 2005
Changchun Institute of Applied Chemistry
Chinese Academy of Science

Publications

• Haiyuan Zhang, Jiu-sheng Wu, Fangyu Peng. Potent anticancer activity of pyrrolidine dithiocarbamatecopper complex against cisplatin-resistant neuroblastoma cells. Anticancer Drugs19(2):125-132(2008)


• Haiyuan Zhang, Ronald Thomas, David Oupicky, Fangyu Peng. Synthesis and characterization of new copper thiosemicarbazone complexes with an ONNS quadridentate system: cell growth inhibition, S-phase cell cycle arrest and proapoptotic activities on cisplatin-resistant neuroblastoma cells. J. Biol. Inorg. Chem. 13:47-55 (2008)


• Haiyuan Zhang, Haijia Yu, Jingsong Ren and Xiaogang Qu. PolydA and PolyrA self-structureed by a europium and amino acid complex.FEBS Letters 580: 3726-3730 (2006)


• Haiyuan Zhang, Haijia Yu, Jingsong Ren and Xiaogang Qu. Reversible B/Z-DNA transition under the low salt condition and non-B-form PolydAPolydT selectivity h by a cubane-like europium-L-aspartic acid complex. Biophy. J. 90: 3203-3207 (2006).


• Haixia Xu, Haiyuan Zhang, Xiaogang Qu. Interactions of the human telomeric DNA with terbium-amino acid complexes. J. Inorg. Biochem. 2006, 100(10): 1646-1652


• Haiyuan Zhang, Jinping Wang, Xin Lu, Kuiyue Yang, Chunji Niu. Effects of praseodymium (III) on zinc (II) species in human interstitial fluid. Biol. Trac. Elem. Rea.107 (2): 101-112 (2005).


• Haiyuan Zhang, Xin Lu, Jinping Wang, Kuiyue Yang, Chunji Niu. Computer simulation of Pr (III) speciation in human interstitial fluid. Chem. Spec. Bioavailab.16(4): 153-158 (2004).


• Wang Jinping, Haiyuan Zhang, Kuiyue Yang, Chunji Niu. Computer simulation of Gd (III) speciation in human interstitial fluid. Biometals. 17(6), 599-603(2004).


• Haiyuan Zhang, Xin Lu, Jinping Wang, Kuiyue Yang, Chunji Niu. Computer simulation for effect of Pr(III) on Ca(II) speciation in human interstitial fluid. Biol. Trac. Elem. Rea. 94(20): 131-140 (2003).


• Wang Jinping, Haiyuan Zhang, Kuiyue Yang, Chunji Niu. Computer simulation of Zn(II) speciation and effect of Gd(III) on Zn(II) speciation in human blood plasma.Biol. Trac. Elem. Rea. 96(1-3): 125-131 (2003).


• Wang Jinping, Haiyuan Zhang, Kuiyue Yang, Chunji Niu. Studies on effect of Gd(III) on Ca(II) species in human interstitial fluid by mathematical mode method. Chem. J. of Chin. Univ. 24(4): 565-568 (2003).


• Wang Jinping, Haiyuan Zhang, Kuiyue Yang, Chunji Niu. Computer simulation of Gd(III) speciation in human interstitial fluid. Chin. Chem. Lett. 14(2): 217-218 (2003).


• Haiyuan Zhang, Xin Lu, Kuiyue Yang, Chunji Niu. Computer simulation of insoluble Pr (III) speciation in human interstitial fluid. Chin. Chem. Lett. 13(7): 658-659 (2002).

Proceeding

• Haiyuan Zhangand Fangyu Peng. Design, synthesis and anticancer activity assay of novel copper complex specifically inhibiting the proliferation of neuroblastoma cell. Division of Medicinal Chemistry, 236th ACS National Meeting, Philadelphia, PA. August 17-21, 2008


• Haiyuan Zhang and Fangyu Peng. Systemic Delivery of Human Copper Transporter 1 Reporter Gene with HIV TAT peptide DNA complexes in Mice. The 5th International Workshop on Drug Delivery Systmes. Trest, Czech. May 15-18, 2007


• Haiyuan Zhang and Fangyu Peng. Synthesis, characterization, and anticancer activity of new copper thiosemicarbazone compound holding ONNS quadridentate system. Division of Medicinal Chemistry, 234th ACS National Meeting, Boston, MA. August 19-23, 2007


• Haiyuan Zhang and Fangyu Peng. Synthesis and characterization of pyrrolidine dithiocarbamate-copper complex: Proliferation inhibition, cell cycle arrest, apoptosis induction activities on cisplatinresistant neuroblastoma cells. Division of Medicinal Chemistry, 234th ACS National Meeting, Boston, MA. August 19-23, 2007

Contact Information

44-116C Engineering IV
420 Westwood Plaza
Los Angeles, CA 90095

Phone:
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UCLA School of Engineering
420 Westwood Plaza
Engineering IV, 33-140
Los Angeles, CA 90024