Dean Ho






 

 

 

 

 

 

 

Currently at Northwestern University

 

 

Research Associate California Institute of Technology
Research Associate University of California at Los Angeles

 

Current Research

1. Biotic-Abiotic Interfacing - Development of advanced biofunctionalized materials for the enhancement of implant biocompability, functionalizing block copolymers with membrane-bound proteins

2. ZnO-based Nanowire Detection of Neural Activity

3. Autonomous C2C12 Cellular Alignment Induced through Interfacial Mechanosensing of Relative Stiffness of Copolymer-Collagen Hybrid
Substrate Materials

Education

University of California at Los Angeles
Ph.D. Biomedical Engineering January 2005
Major: Molecular and Cellular Bioengineering
Minor: Microelectromechanical Systems (MEMS)
Minor: Engineering Mechanics of Motor Proteins

M.S. Biomedical Engineering June 2003
B.S. Physiological Science December 2001

Publications

JOURNAL PAPERS

  1. J. Huang, A. Shalchi, D. Ho, Y.H. Zhang, E. McCabe, and C.M. Ho, “Rapid Bacterial Diagnosis-MEMS-based DNA Detection,” Pediatric Research 51 (4) 1610, 2002.


  2. D. Ho, B. Chu, J.J. Schmidt, J., Brooks, E., Montemagno, C.D., “Hybrid Protein/Polymer Biomimetic Membranes,” IEEE Trans. Nanotechnology, 3 (2), 256-263, June 2004.


  3. D. Ho, B. Chu, H. Lee, and C.D. Montemagno, “Protein-driven Energy Transduction Across Polymeric Biomembranes,” Nanotechnology 15 (8), 1084-1094, August 2004 Article downloaded over 1000 times; top 10% of all Institute of Physics (IOP) Publications (Information as of July 2005). Nanotechnology is ranked #1 in impact factor by ISI among Multidisciplinary Engineering Journals, and top 10 in Applied Physics.


  4. D. Ho, and C.D. Montemagno, “The Advent of Innovation-Societal Perspectives of the Integrative Nanotechnology Revolution,” published online at Institute of Physics website, www.nanotechweb.org; in press, Nanotechnology, March 2005.


  5. J. Xi, D. Ho, B. Chu, and C.D. Montemagno, “Lessons Learned From Engineering Biologically-Active Hybrid Nano/Micro-devices,” Advanced Functional Materials 15 (8), 1233-1240, July 2005. Feature Article Journal ranks #3 in Applied Physics and #6 in Materials Science-Multidisciplinary in impact factor by ISI.


  6. D. Ho, B. Chu, H. Lee, E.K. Brooks, K. Kuo, and C.D. Montemagno, “Light-Dependent Current Generation Based on Coupled Protein Functionality,” in review, Nature Biotechnology, August 2005.


  7. H. Lee, D. Ho, and C.D. Montemagno, “Fluorometric Measurement of Vectorially-Inserted Purple Membrane Activity Across Block Copolymer Thin Films,” in review, Nanotechnology


  8. D. Ho, A. Fung, and C.D. Montemagno, “Engineering Novel Diagnosis Modalities and Biofunctional Nanomaterials for Next Generation Medicine,” accepted to Biology of Blood and Marrow Transplantation, September 2005. Invited Paper


  9. D. Ho, S. Chang, and C.D. Montemagno, “Fabrication of biofunctional nanomaterials via Escherichia coli OmpF protein air-water interface insertion/integration with copolymeric amphiphiles,” submitted to Nanomedicine, September 2005.


  10. D. Ho, D. Garcia, and C.M. Ho, “Using Advanced Nanomanufacturing and Characterization Modalities Towards the Realization of Bio-Nano-Informatics Systems,” submitted to Journal of Nanoscience and Nanotechnology, September 2005.


  11. D. Ho, and Y. Chen, “Interfacing Cellular Systems with Abiotic Materials Using Composite Collagen-Block Copolymer Thin Films,” submitted to Nanotechnology, September 2005.


  12. D. Ho, and Y. Chen “Block copolymer-collagen Type I composite substrates induce striation in C2C12 skeletal myoblasts,” to be submitted to Proceedings of the National Academy of Sciences-USA, 2005


  13. D. Garcia, J. Jue, and D. Ho, “MEMS and NEMS Technologies: Technology and Markets,” in preparation Journal of Nanotechnology Law and Business, 2005.


  14. D. Ho, B. Chu, H. Lee, K. Kuo, and C.D. Montemagno, “ Enhancing Conversion Efficiencies of Light-Dependent Proton Pumps Using Quantum Dot Nanocrystals,” in preparation, 2005.


  15. 15. B. Chu, D. Ho, H. Lee, K. Kuo, and C.D. Montemagno, “Composite Proton Exchange Membranes Functionalized with Biomolecules Reduce Methanol Crossover and Electro-osmotic Drag,” in preparation, 2005.


REFEREED CONFERENCE PAPERS

  1. D. Ho, J.J. Schmidt, and C.D. Montemagno, “Protein/Polymer Hybrid Biomimetic Valves,” Proceedings of the Materials Research Society, 735 C.4.5.1-C.4.5.4 (2003)


  2. D. Ho, and C.D. Montemagno, “Hybrid Protein/Polymer Biomimetic Membranes,” IEEE Proceedings on Nanotechnology (1), 379 –382, August 2003


  3. H. Lee, D. Ho, J.J. Schmidt, and C.D. Montemagno, “Biosolar Powered Fabric,” IEEE Proceedings on Nanotechnology (2), 733 –736, August 2003


  4. D. Ho, B. Chu, H. Lee, and C.D. Montemagno, “Directed Protein Adsorption by Site-specific Labeling,” IEEE Proceedings on Nanotechnology (2), Special Paper Session Paper Suppl. 2003


  5. . D. Ho, B. Chu, and C.D. Montemagno, “Nanoscale Hybrid Protein/Polymer Functionalized Devices,” Proc. SPIE Int. Soc. Opt. Eng. 5389, 192 (2004)


  6. D. Ho, B. Chu, K. Kuo, and C.D. Montemagno, “Functionalizing Biomimetic Membranes with Energy Transducing Proteins,” Proc. of the Mat. Res. Soc. 823, W11.8.1-W11.8.6, 2004


  7. D. Ho, B. Chu, H. Lee, K. Kuo, and C.D. Montemagno, “ Fabrication of Hybrid Bionanodevices Based on Coupled Protein Functionality,” Proc. ASME NANO, Pasadena, CA September 22-24, 2004


  8. D. Ho, B. Chu, H. Lee, K. Kuo, and C.D. Montemagno, “ Electrochemical Measurement of Coupled Protein Functionality Across Polymer Membranes,” Accepted to Proc. Electrochem. Soc.- Intl. Symp. on Nanoscale Devices, Materials, and Biological Systems: Fundamentals and Applications, Vol. AH1, 2004


  9. B. Chu, D. Ho, H. Lee, K. Kuo, and C.D. Montemagno, “Enhancing Proton Exchange Membrane Functionality with Biomolecules,” Accepted to Proc. Electrochem. Soc.- Intl. Symp. on Nanoscale Devices, Materials, and Biological Systems: Fundamentals and Applications, Vol. AH1, 2004


  10. B. Chu, D. Ho, H. Lee, K. Kuo, and C.D. Montemagno, “Protein-Functionalized Proton Exchange Membranes,” Proc. ASME NANO, Pasadena, CA September 22-24, 2004


  11. H. Lee, D. Ho, B. Chu, K. Kuo, and C.D. Montemagno, “ Reconstituting Biomolecules into Artificial Membranes and Detection of their Activities,” Proc. ASME NANO, Pasadena, CA September 22-24, 2004


  12. H. Lee, D. Ho, B. Chu, K. Kuo, and C.D. Montemagno, “ Membrane Proteins in Artificial Systems,” Accepted to Proc. Electrochem. Soc. Intl. Symp. on Nanoscale Devices, Materials, and Biological Systems: Fundamentals and Applications, Vol. AH1, 2004.


  13. D. Ho, B. Chu, H. Lee, K. Kuo, and C.D. Montemagno, “Synthesis and Characterization of Biomolecular Hybrids as Energy Conversion Systems,” International Symposium on Environmental Nanotechnology 2004, Taipei, Taiwan, December 1st, 2004.


  14. D. Ho, B. Chu, H. Lee, K. Kuo, and C.D. Montemagno, “Coupled-Protein Functionality for Energy Conversion in Biomimetic Systems,” accepted to IEEE Robio Conference, Hong Kong, June 28-July 3, 2005.


  15. D. Ho, B. Chu, H. Lee, K. Kuo, E.K. Brooks, and C.D. Montemagno, “Light-Dependent Current Production Using Biofunctional ABA Triblock Copolymers,” Bio-Nano-Information Fusion, Marina Del Rey, California, July 20, 2005.


  16. D. Ho, and Y. Chen, “Interfacing Cellular Systems with Abiotic Materials Using Composite Collagen-Block Copolymer Thin Films,” Bio-Nano-Information Fusion, Marina Del Rey, California, July 20, 2005.

Meeting Abstracts and Presentations

INVITED TALKS

  1. Bionanotechnology: Academic and Industrial Partnerships in the UK and US, “Hybrid Nanotechnology,” University of Southern California, June 10th, 2004


  2. California Nanosystems Institute (CNSI) Invited Talk, “Fabrication of Biomolecule-Copolymer Hybrids as Energy Conversion Systems”, University of California, Santa Barbara, February 18, 2005


  3. Academia Sinica (National Academy of Sciences), “ Light-Dependent Current Generation from Biofunctionalized ABA Triblock Copolymers,” Taipei, Taiwan, June 22, 2005.


PRESENTATIONS

  1. D. Ho, J.J. Schmidt, E.K. Brooks, and C.D. Montemagno, Engineering Pore Proteins as Nanoscale Microfluidic Valves, NM2- Conference on Molecular Mechanics, Scholarship Recipient, Poster Presentation, Maui, HI, May 12-17, 2002


  2. D. Ho, J.J. Schmidt, E.K. Brooks, and C.D. Montemagno, Engineering Pore Proteins as Nanoscale Microfluidic Valves, California Nanosystems Institute (CNSI) Poster Symposium, 2002


  3. D. Ho, B. Chu, J.J. Schmidt, E.K. Brooks, and C.D. Montemagno, “Engineering Pore Proteins as Nanoscale Macromolecule Sensors”, University of California Systemwide Bioengineering Symposium, San Diego, CA, June 21-23, 2003. Best Poster Presentation Award Winner


  4. D. Ho, B. Chu, and C.D. Montemagno, “Nanoscale Hybrid Protein/Polymer Functionalized Devices,” SPIE Meeting on BioMEMS and Nanotechnology. March


  5. D. Ho, B. Chu, H. Lee, and C.D. Montemagno, Functionalizing Nanoscale Polymeric Biomimetic Membranes with Energy Transduction Proteins, CESASC Annual Convention, May 22, 2004.


  6. D. Ho, B. Chu, H. Lee, and C.D. Montemagno, “Synthesis and Characterization of Biomolecule-Copolymer Hybrids as Energy Conversion Systems,” CESASC Annual Convention, April 22, 2005.


Contact Information

California Institute of Technology
1200 E. California Blvd.
Mail Code: 136-93
Pasadena, CA 91125

Phone:
E-mail: deanh@caltech.edu